ANTI HUMAN LXR ALPHA
PP-K8607-00
1
Brand
Iwai North America
Description
Liver X receptor alpha (LXRa, RLD-1; NR1H3) is a member of orphan nuclear receptor. LXRa activator is the naturally occurring compound 22(R)- hydroxycholesterol (22(R)-HC), 20(S)HC, 24-HC, 25- HC, 7a-HC. LXRa is expressed in the liver, kidney and spleen. LXRa has important role in regulating cholesterol metabolism. It is believed that LXR specific agonist may have important medical applications in the regulation of cholesterol homeostasis. LXRa forms heterodimer with RXR.
Application
IPWB
Reactivity